Roads in several areas, including an exit from Interstate 95 in Baltimore, were closed because of high water. Baltimore transportation officials also reported northbound I-295 between I-695 and I-95 and southbound I-295 between I-95 were also closed as of 7 a.m.
Wednesday evening, city firefighters rescued at least three more people from cars trapped in the floodwaters, said Sam Johnson, the department spokesman.
The powerful storm system swept across the East Coast on Wednesday, killing four people in Virginia and knocking out power to tens of thousands of homes and businesses in the region.
In Harford County, firefighters rescued three people from cars on flooded roads. On Facebook, the department urged drivers to avoid the risk of crossing the water.
Central Maryland was under a tornado watch throughout the evening. Some parts, including St. Mary's County, were under tornado warnings.
At 11 p.m., storm winds had knocked out power for nearly 2,500 people throughout Maryland, according to the Baltimore Gas and Electric Co. outage map.
Thursday morning, about 600 outages remained across the state.
Funnel clouds were reported Wednesday in Stafford and Fredericksburg, Virginia, said Dan Hofmann, a meteorologist with the National Weather Service.
Fire officials in Montgomery County in Maryland say a man was rescued after a basement wall collapsed on him in a Silver Spring home Wednesday night.
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Baltimore sun reporter Scott Dance and The Associated Press contributed to this report.