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Columbia biotech company that makes skin substitutes is sold to a London-based firm

Columbia biotech company that makes skin substitutes is sold to a London-based firm

The sale of one of Maryland’s most promising, but also once-troubled biotechnology companies, Osiris Therapeutics Inc., to a British medical equipment maker is complete, the Columbia-based company announced.

Smith & Nephew plc paid $660 million for Osiris, which focuses on developing and marketing stem cell-based, or regenerative medicine, products for wound care, orthopedics and sports medicine.

About 70 percent of the company’s revenue comes from two products. That includes Grafix, a human skin substitute used...

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