Bears quarterback Jay Cutler makes his first start since he strained a hamstring in the first half of a 48-23 loss to Arizona on Sept. 20. He will be without one of his favorite targets in wide receiver Alshon Jeffery, who is out for the third straight week with a hamstring injury.
JACKSONSVILLE AT INDIANAPOLIS
Colts: QB Andrew Luck, CB Greg Toler, RB Tyler Varga, DT T.Y. McGill, OT Denzelle Good, G Todd Herremans, TE Dwayne Allen.
Jaguars: WR Marqise Lee, RB Denard Robinson, S Sergio Brown, G Brandon Linder, TE Julius Thomas, DE Chris Smith, DT Sen'Derrick Marks.