DENVER - Another week, another milestone for Peyton Manning.
Manning became the second quarterback in NFL history to throw for 500 touchdowns in Sunday's game against the Arizona Cardinals.
Manning hooked up with tight end Julius Thomas for a 7-yard score on 3rd-and- goal at the 4:43 mark of the first quarter to get to the 500 mark.
Brett Favre holds the all-time record of 508 TD passes.
Peyton Manning throws 500th career TD pass
Denver Broncos fans hold up signs to celebrate the 500th career touchdown pass by quarterback Peyton Manning. (Justin Edmonds / Getty Images)