The 32-year-old immediately grabbed his left hamstring before going to the ground on a 3rd-and-6 play from the Cincinnati Bengals' 7-yard line. Joe Flacco's pass, which was intended for Woodhead, fell incomplete and Justin Tucker put the Ravens on the board with a field goal on the next play.
Woodhead had a big first drive with three catches for 33 yards and one carry for four yards.
Early in the second quarter, outside linebacker Za'Darius Smith appeared to sustain a potentially significant left leg injury. He was helped off the field unable to put any weight on his left leg and ultimately carted back to the locker room.