Jackson was replaced by former Miami Dolphins cornerback Rashaan Melvin, who played well in his first NFL game with five tackles, one for a loss and a pass deflection. He effectively shadowed Jaguars wide receivers despite a lack of experience.
"Melvin came in there and did a great job and played really well and was excited to get out and get a chance," Harbaugh said. "The next guy has to step up, and they will. This is a team sport, and our guys have done a good job with that so far, and they'll keep doing it."