2. One of the best. Ramirez will be pitching opposite Red Sox left-hander Chris Sale, one of the best in the game. Sale is coming off perhaps his best start of the season, in which he allowed one run on six hits while striking out 10 in eight innings. That followed his only rough patch of 2018 — a two-start stretch in which he gave up 10 runs in 10 1/3 innings. Outside of that, the six-time All-Star has held teams to three runs or fewer in each of his other 12 starts this season.