2. Cy Sale. Red Sox lefty Chris Sale looks to punctuate what he hopes will be credentials worthy of his first Cy Young Award. Sale comes in leading the majors with 201 1/3 innings and is second in the American League with a 2.86 ERA. Sale struggled his last time out, allowing four runs in 5 2/3 innings. The Orioles have faced him twice this season, managing five runs in 14 innings while striking out 20 times compared to just three walks.