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Orioles (17-38) vs. Nationals (31-22)

Where: Camden Yards

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First pitch: 7:05 p.m.

TV/Radio: MASN/105.7 The Fan

Starting pitchers: Orioles RHP David Hess (2-1, 4.15 ERA) vs. Nationals RHP Max Scherzer (8-1, 2.13 ERA)

What to watch

1. Scherzer. Two-time defending Cy Young Award winner Max Scherzer is well on his way to challenging for a third straight honor as he takes the mound at Camden Yards for Wednesday’s series finale. Scherzer leads the majors in wins and ranks second in strikeouts (108), fourth in opponents’ batting average (.180), fifth in ERA and fifth in WHIP (0.91). He’ll be looking to rebound from his worst start of the season in which he allowed four runs in six innings but beat the Miami Marlins anyway. Before that, he had a 1.78 ERA through 10 starts. Just three Orioles enter the game batting above .200 in their careers against Scherzer — Adam Jones (.412, four homers), Chris Davis (.313) and Danny Valencia (.250).

2. Hess. Rookie Davis Hess makes his fourth career start Wednesday and will be looking for his first good outing against a team that isn’t the Tampa Bay Rays. Both of Hess’ quality starts (and wins) came against the Rays. Hess struggled against the Boston Red Sox, owners of the best offense in baseball, in his other start. In his most recent outing, the 24-year-old was as good as he’s been, allowing four hits and walking three in 6 2/3 scoreless innings at Tropicana Field. He’ll be looking to do it again as he’s well on his way to solidifying a spot in the Orioles rotation.

3. Still searching. The Orioles look to avoid being swept by the Nats as the schedule has ramped back up in difficulty. Starting with this series, the Orioles play nine of 11 series against teams with records of .500 or better entering Wednesday. That includes nine straight games that began with this series and 15 straight beginning June 19. The Orioles are already off to their worst 55-game start since 2010, when they began 15-40, and the upcoming schedule threatens to make things much worse. Having lost four straight, can they begin to break out of it Wednesday?

Orioles lineup

3B Jace Peterson

CF Adam Jones

SS Manny Machado

2B Jonathan Schoop

DH Mark Trumbo

1B Chris Davis

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LF Trey Mancini

C Chance Sisco

RF Joey Rickard

Nationals lineup

LF Juan Soto

SS Trea Turner

RF Bryce Harper

3B Anthony Rendon

DH Matt Adams

1B Mark Reynolds

CF Michael A. Taylor

2B Wilmer Difo

C Pedro Severino

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