Reynaldo Lopez was facing baseball's hottest team with a defense behind him that wasn't at the top of its game Wednesday night at Guaranteed Rate Field.
So holding the Indians to one earned run over six innings was a big success for the rookie right-hander in his fourth White Sox start.
Lopez gave up six hits with two walks and two strikeouts, but the Sox couldn't solve Indians right-hander Carlos Carrasco in a 5-1 loss. Carrasco pitched a three-hitter on 97 pitches to help the Indians extend their winning streak to 14 games, tied for a franchise record. He struck out nine and gave up the only run on Adam Engel's homer with two out in the ninth.
Lopez pitched around a couple of jams partially created by defensive miscues.
He loaded the bases in the fourth on a walk and a pair of singles that left fielder Nicky Delmonico and second baseman Alen Hanson couldn't make plays on. But he held the Indians to only a run on Tyler Naquin's sacrifice fly to left field. It was Lopez's third quality start since he was called up Aug. 11.
"They are going to have good days and bad days, and they are going to make some mistakes once in a while," Lopez said of the defense through an interpreter. "I believe in them because I know they are trying to do their best. … How did I keep my focus? I just worked on executing my plan."
Carlos Santana hit a two-run homer off reliever Danny Farquhar in the eighth, and the Indians added a run on Matt Davidson's second error of the game.
Carrasco opened the game with four perfect innings and held the Sox to just two baserunners over the first eight.
"(Carrasco's) ball had a lot of action today," Sox manager Rick Renteria said. "All in all, as much as (Lopez) threw well, the game just didn't look very clean."
Lineup in flux: The Sox reinstated Delmonico from the disabled list, where he was since Aug. 25 with a sprained right wrist. Yoan Moncada came off the DL on Tuesday, but Renteria rested him Wednesday as he returns to playing without a rehab assignment.
Shortstop Tim Anderson was scratched because he wasn't feeling well, and Delmonico exited in the ninth after he tweaked his left shoulder.
Storm worries: Renteria said he knows many of his players' minds and hearts will be with their families as Hurricane Irma potentially could affect their homes in Puerto Rico, the Dominican Republic, Cuba and Florida. Renteria said much of his wife's family is in Puerto Rico.
"It keeps everything in perspective, all of the things that are going on, the things that just happened in Houston," Renteria said. "We're all cognizant of the realities of life and the things that are really important. There are going to be a lot of people keeping track."
On the farm: The Class A Kannapolis South Atlantic League playoff opener Wednesday was postponed because of rain. Pitching prospect Dylan Cease was scratched from his start in that game because of shoulder fatigue, but the Sox expect Cease to pitch in instructional league this fall.