And that was just part of an amazing night for Henry.
Henry tied Tony Dorsett's 99-yarder on Jan. 3, 1983, for Dallas against Minnesota for the longest TD run in NFL history. Henry ran to his left and ran up the sideline, stiff-arming first Jaguars cornerback A.J. Bouye, then rookie linebacker Leon Jacobs twice and finally a shove to linebacker Myles Jack to finish off the TD.
The 2015 Heisman Trophy winner, celebrated by striking the Heisman pose not once, but twice.
Henry set a franchise record with 238 yards on just 16 carries, topping the previous mark of 228 yards set by Chris Johnson in 2009 against yes, the Jaguars.
Henry finished with a career-high four TDs, tying Lorenzo White and Hall of Fame running back Earl Campbell for most rushing TDs in a single game in franchise history. Henry also became the first player in the NFL with four rushing TDs in a game since Jonas Gray of the Patriots in Week 11 in 2014.
Titans coach Mike Vrabel called Henry's night “very impressive.”
With the rout and second win in a row, the Titans (7-6) stayed in AFC playoff contention with their fourth straight victory over their oldest division rival. They've won six of their last seven against Jacksonville.
The Jaguars (4-9) have lost eight of their last nine.
Johnson called Henry's 99-yarder “amazing” and congratulated Henry after passing him for the team record.
Marcus Mariota, wearing black tape on the back of his right hand, threw for 162 yards. The Titans outgained the Jaguars 426-255, and they also had four sacks.
Jacksonville came in with the league's fifth-best scoring defense after shutting out Andrew Luck for the first time in the NFL. But Jacksonville has been susceptible against the run, ranked 16th giving up 108.4 yards. Henry nearly matched that on his record-tying run.
Henry's TD capped a huge swing over two plays.
Titans rookie Cameron Batson muffed the punt at the Titans 7 before recovering at the 1 and being tackled in the end zone for a safety. The Jaguars took the ensuing free kick and drove downfield where they picked up a fourth-and-1 at the Titans 5. Then the Titans stopped the Jaguars on the next four plays, the last with rookie linebacker Rashaan Evans tripping up Leonard Fournette.
On the very next play, Henry started toward the middle before turning left for a TD run where he simply couldn't be stopped. Henry had 129 yards on six carries with two TDs all by halftime to become the Titans' first 100-yard rusher this season. Before his night ended, he added TD runs of 16 and 54 yards .