Yale 10, No. 8 Penn State 7: After trailing by four at halftime, the visiting Bulldogs (12-4) exploded out of the break and outscored the Nittany Lions 9-2 in the second half to advance to the second round.
Penn State (12-5) won all seven faceoffs in the first half and scored five unanswered goals to take a 5-1 halftime lead, but Yale started to click offensively in the second half and tied the game at 6 with 12:59 left.
The Bulldogs went on a 7-0 run through the final two quarters and led by as many as four in the fourth. Penn State turned the ball over nine times in the last period.
Colin Flaherty led the Bulldogs with three goals, and Eric Natale had 10 saves as Yale earned its first NCAA tournament victory since 1992.
The Bulldogs will play top-seeded Syracuse or Bryant in the quarterfinals next weekend in College Park.
No. 4 Denver 19, Albany 14: Wesley Berg scored a career-high eight goals to lead the host Pioneers (13-4) into the second round over the unseeded Great Danes (13-5).
After trailing by one in the first quarter, Denver finished the first half on a 6-2 run to take a 9-6 lead into halftime.
With one second left in the third quarter, Eric Law caught a long pass from Taylor Long and scored to give Denver a five-goal lead into the fourth. Law, a transfer from Salisbury, finished with four goals.
Denver will play next Sunday against North Carolina.
No. 5 North Carolina 16, Lehigh 7:Marcus Holman (Gilman) had a goal and four assists as the Tar Heels (13-3) finished on a 7-1 run to take down the visiting Mountain Hawks (12-5) in the first round.
The Sea Gulls scored the only goal of the third quarter before the Generals scored twice in the fourth quarter to trail 6-4. Brady Dashiell scored with 2:30 left to give Salisbury a three-goal cushion they would not relinquish.
Salisbury will play Wednesday against Dickinson, which beat Adrian, 20-7.
Salisbury 17, Christopher Newport 5: The host Sea Gulls (20-0) dominated the first half and used a 12-3 halftime lead to beat the Captains (18-3) in the second round of the NCAA tournament.
Salisbury scored six unanswered goals to start the game.