Kelly McPartland had a game-high six goals for the host Terps (12-0). Gabby Cha (Mount de Sales) gave the Tigers (5-5) a 1-0 lead 2:09 into the game before Maryland answered with a 5-0 run.
Towson's Taylor Moore had a natural hat trick to pull Towson within 5-4 with 13:22 left in the first half.
Loyola's Annie Thomas had two goals and an assist.
Salisbury 9, Colby 7: Behind a three-goal effort from Shannon Carta (South River) and Bethany Baer (Westminster), the host Sea Gulls (9-0) set a school record with 33 straight home wins.
The Mules fell to 3-3.
Marymount 13, Goucher 10: The visiting Gophers (6-5) had a two-game winning streak halted by the Saints (5-2).
Rita Meissner had four goals for Goucher. Marymount won 18 of 24 draws to control the tempo of the game.
Frostburg State 14, La Roche 3: The visiting Bobcats (8-2) used a strong second half to beat the Redhawks (2-4).
Frostburg State, led by Ryan Serio (Chesapeake-AA) with a career-high seven goals, outscored La Roche, 9-0, in the second half.
Dickinson 10, McDaniel 3: The host Red Devils (4-4, 1-0 Centennial Conference) scored the first five goals of the game and the final four to beat the Green Terror (3-6, 0-2).
Washington College 14, Haverford 5: The host Shoremen (7-1, 2-0 Centennial), led by Jim Cusick (Calvert Hall) with four goals, opened with a 10-0 run over the Fords (1-7, 0-2) that spanned three quarters.
Messiah 12, Hood 2: The host Falcons (3-4, 1-0 Commonwealth Conference) scored seven goals in the first quarter and the Blazers (3-5, 0-1) never recovered.
No. 1 North Carolina 21, Virginia Tech 9: Aly Messinger and Abbey Friend scored five goals each to lead the host Tar Heels (11-0, 4-0 Atlantic Coast Conference) past the Hokies (5-5, 0-3).
The defending NCAA champions led 4-0 after five minutes of play. Taylor George (Broadneck) had four goals for Carolina.
No. 5 Florida 23, Stetson 1: Shanon Gilroy had seven goals and the visiting Gators (11-2) led 13-0 before the Hatters (0-12) scored with one second left in the first half.
No. 12 Penn State 21, Drexel 8: Madison Cyr (Winters Mill) had four goals and an assist and the host Nittany Lions (7-3) jumped out to a 6-0 lead over the Dragons (4-6) and never looked back.
No. 17 Ohio State 13, Oregon 9: Katie Chase (Glenelg) had a career-high seven goals and an assist to power the host Buckeyes (7-4) past the Ducks (4-4). During a 5-0 run in the second half, Chase scored three.
No. 20 Virginia 19, Old Dominion 8: Liza Blue (Garrison Forest) had five goals and Liz Colgan (Notre Dame Prep) made six saves as the host Cavaliers (5-6) beat the Monarchs (3-7).