Reed had 20 points, Paris Maragkos had a career-high 17 and Delante Jones 11 for the Eagles (2-10, 0-1).
No 11 Iowa State 104, Coppin State 84: Abdel Nader led six players in double figures with 21 points and the host Cyclones (11-1) cruised past the Eagles (2-13).
Deonte Burton scored 17 points for Iowa State, which opens its conference schedule at No. 3 Oklahoma on Saturday.
The Cyclones went ahead by 21 points midway through the first half and won by at least 20 for the sixth time. Monte Morris had 10 points with 11 assists for his fourth doubledouble of the year for Iowa State.
Josh Treadwell had 21 for Coppin State (2-13), which lost its 11th straight.
Iowa State, which notched an unimpressive win over Arkansas-Pine Bluff in its last home game, opened the game on a 12-0 run. The Cyclones then scored 10 of 11 points — with their players at times looking surprised at how open they were on offense — to go ahead 30-9.
Bucknell 88, Navy 58: Chris Hass scored 22 points and the host Bison (4-8) ended a seven-game losing streak by defeating the Mids (9-5) in a Patriot League opener.
Hass was 8-of-12 from the field and made three 3-pointers. Stephen Brown added a career-high 18 points and eight assists. Bucknell shot 54 percent, making 9 of 20 3-point tries.
Navy's Shawn Anderson was 7-of-9 from the field for 19 points.
The Bison avoided their first eight-game losing streak since the 2008-09 season in beating the Midshipmen for the fourth straight time.
Navy came in ranked 12th in scoring defense, giving up just under 60 points per game, but the Bison, who never trailed and led, 42-29, at halftime, dealt the Mids their worst defeat this season.
Loyola Maryland 52, American 46: Colleen Marshall scored a game-high 17 points, including the game-winning 3-pointer with 1:32 to play, as the host Greyhounds (4-8, 1-0 Patriot League) beat the Eagles (2-10, 0-1).
Jeneh Perry helped Marshall offensively, adding 12 points for Loyola, while senior Steph Smith finished with a game-high eight rebounds.
Towson 70, Missouri-Kansas City 47: The host Tigers (3-8) strung together a 21-point second quarter and a 20-point third quarter to lead them past the Kangaroos (4-8).