Pro football reporter Sam Farmer breaks down the games.
Last week's record: 7-7 Against the spread: 7-7
Season: 50-40 Against the spread: 41-49
Off: Lions, Texans, Colts and Jets
Noon Eagles (4-2) at Titans (4-2)
Line: Titans by 3 Over/under: 43
Losing DeSean Jackson hurts, but Eagles still have enough receiving weapons to test so-so Titans secondary.
Pick: Eagles 30, Titans 24
Noon Steelers (4-1) at Dolphins (3-2)
Line: Steelers by 3 Over/under: 40 1/2
If Steelers can establish run, they will try to hit Dolphins over top with Mike Wallace, who's plenty fast enough to stretch field.
Pick: Steelers 20, Dolphins 15
Noon Jaguars (3-3) at Chiefs (3-2)
Line: Off board Over/under: Off
Chiefs should be able to regain defensive legs against inconsistent Jaguars, who are hitting road after short week.
Pick: Chiefs 27, Jaguars 24
Noon Bengals (2-3) at Falcons (4-2)
Line: Falcons by 3 1/2 Over/under: 42 1/2
Matt Ryan is 15-1 at home and Falcons should bounce back after disappointing performance vs. visiting Eagles.
Pick: Falcons 24, Bengals 20
Noon Rams (3-3) at Buccaneers (3-2)
Line: Bucs by 3 Over/under: 38
Pick: Rams 20, Bucs 17
Noon Bills (0-5) at Ravens (4-2)
Line: Ravens by 13 Over/under: 39 1/2
This could be trap game for Ravens, but it's unlikely they will lose that much focus at home, and Bills don't have much firepower.
Pick: Ravens 30, Bills 17
Noon Browns (1-5) at Saints (4-2)
Line: Saints by 13 Over/under: 43
These aren't same Saints who rumbled through 2009. But winning in New Orleans is still tough, especially for team like banged-up Browns.
Pick: Saints 35, Browns 17
Noon 49ers (1-5) at Panthers (0-5)
Line: 49ers by 3 Over/under: 35 1/2
Panthers are switching back to Matt Moore, who had six turnovers in first two games. That's how bad things have gotten.
Pick: 49ers 17, Panthers 9
Noon Redskins (3-3) at Bears (4-2)
TV: WFLD-Ch. 32
Line: Bears by 3 Over/under: 40
Blocking Redskins' 3-4 defense — and especially keeping Brian Orakpo at bay — will be tall order for porous Bears offensive line.
Pick: Redskins 21, Bears 17
3:05 p.m. Cardinals (3-2) at Seahawks (3-2)
Line: Seahawks by 5 1/2 Over/under: 40 1/2
Pete Carroll has players believing in themselves, especially at home where they're 2-0. Tough place for Max Hall to make road debut.
Pick: Seahawks 28, Cardinals 21
3:15 p.m. Patriots (4-1) at Chargers (2-4)
TV: WBBM-Ch. 2
Line: Chargers by 2 1/2 Over/under: 47
Health of tight end Antonio Gates is huge. If Philip Rivers doesn't have him, Chargers' offense really handcuffed.
Pick: Patriots 28, Chargers 24
3:15 p.m. Raiders (2-4) at Broncos (2-4)
Line: Broncos by 8 Over/under: 41 1/2
With Knowshon Moreno back to health, Broncos should be able to control pace and clock against up-and-down Raiders.
Pick: Broncos 17, Raiders 14
7:20 p.m. Vikings (2-4) at Packers (3-3)
TV: WMAQ-Ch. 5
Line: Packers by 3 Over/under: 44 1/2
Brett Favre is big story, of course, but huge factor for Packers will be health of linebacker Clay Matthews, who can be incredibly disruptive.
Pick: Packers 27, Vikings 24
7:30 p.m. Monday Giants (4-2) at Cowboys (1-4)
Line: Cowboys by 3 Over/under: 44 1/2
Giants are rolling, Cowboys are reeling, so this should be an easy victory for Giants, right? Division rivalries often head different direction.
Pick: Cowboys 34, Giants 28