Neither team shot better than 39 percent in the first half, but the Tigers made five of eight from 3-point range to take a 31-29 lead into the break.
Towson extended its lead early in the second half and pulled away when Burwell scored seven points in 1:34 to fuel a 9-0 run.
The Tigers shot 42.9 percent from the field overall and finished 6-for-12 from 3-point range.
Stevenson 79, Lycoming 74: Darius Walker (Edmondson) scored a team-high 24 points and the visiting Mustangs (12-3, 7-1 Commonwealth Conference) scored the game's final six points to defeat the Warriors (7-7, 3-5).
Lycoming rallied from 19 points down at the half to tie the score at 56 with 9:47 left.
Dominique Johnson led Towson with 27 points and set a school record with eight 3-pointers.
A 3-pointer by Johnson cut the Seahawks' lead to two with 1:17 to go. The Seahawks didn't score on their next possession, and Johnson was fouled on her way to the basket, giving the Tigers a chance to tie the game. She missed the first foul shot and made the second, making it 54-53 with 11 seconds remaining.
Towson scrambled to score in the final seconds, but a 3-point attempt by Johnson and a jumper by LaTorri Hines-Allen missed.
Boston University 70, Loyola Maryland 60: A game- and career-high 28 points for Nai Brown weren't enough as the host Greyhounds (4-13, 1-5 Patriot League) lost to the Terriers (7-12, 2-4).
Loyola trailed 9-0 before scoring its first basket 4:37 into the game. The deficit grew to 14 points before the Greyhounds rallied to go into halftime down 28-22.
Loyola came within two points twice during the second half.
Lycoming 66, Stevenson 61: The visiting Mustangs (8-7, 6-2 Commonwealth) cut a 22-point second-half deficit to five but lost to the Warriors (7-7, 4-4) and dropped into a second-place tie with Elizabethtown.
Stevenson's Kayla Kelly (Centennial) scored a team-high 16 points and added seven rebounds, two assists and two steals.