These two teams will meet for the 18th time, but for the first time since 2010. Loyola owns a 12-5 lead in the series, but Notre Dame has won the last four meetings. These teams faced each other in the NCAA tournament just once with the Greyhounds enjoying a 21-5 thumping in the first round on May 11, 1997. The No. 4 seed Fighting Irish (13-2) defeated Yale, 13-7, in the first round and No. 5 seed Virginia, 12-10, in the quarterfinals. No. 1 seed Loyola (16-1) beat Canisius, 17-5, in the first round and Denver, 10-9, in the quarterfinals. Here are a few factors that could influence the outcome of this NCAA tournament semifinal at Gillette Stadium in Foxborough, Mass., Saturday afternoon.