The 6th District, which stretches from Montgomery and Frederick counties through Western Maryland, was by far the state's most competitive House contest in 2014. Delaney narrowly won reelection that year, besting Republican nominee Dan Bongino by less than 2 percentage points.
Sensing vulnerability, Republicans recruited Hoeber to challenge Delaney this year. She ran an aggressive campaign focused in part on Delaney's support for President Barack Obama's controversial Iran nuclear deal.
A super PAC funded by Hoeber's husband invested more than $3 million in advertising on her behalf.
Hoeber told supporters gathered in Frederick that the 16 months she spent campaigning were "amazing," and that the transportation plan she worked out with Republican Gov. Larry Hogan would have lasting effects in the district, if enacted.
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He has antagonized Hogan on policy and political issues. He paid for a mobile billboard to circle the State House in March to challenge the governor to take a position on the candidacy of Donald Trump.
The 8th House District race also featured Libertarian David L. Howser and Green Party candidate George Gluck.
All eight of Maryland's House seats were on the ballot in Maryland Tuesday. The state's six incumbents — five Democrats and one Republican — all won reelection.