Tapp-Harper and other police officials urged people to call in the license plate numbers of motorists seen meeting with suspected prostitutes.
The highest concentration of trangender prostitution is between 20th and 25th streets on St. Paul, Charles and Calvert Street in the Old Goucher neighborhood, police said.
Peter Duvall, Old Goucher Community Association president, said people on crime walks at midnight in the neighborhood have witnessed conversations that they suspected were between prostitutes and would-be clients.
Other residents at the meeting complained about cars honking and other loud noise that they associate with trangender prostitution.
Tapp Harper cited 42 arrests this year for prostitution in general, but said she couldn't immediately provide a breakdown of how many involved transgenders.
Some residents said the problem appears intractable, and asked for more drastic measures, like posting tag numbers on the Internet.
A follow-up meeting is being planned for January to discuss community strategies to fight the prostitution problem, said Diana Mitchell, of the Charles Village Community Benefits District.
Resident Odette Ramos, who ran unsuccessfully for City Council this year, offered to convene a meeting with some transgenders, who she said complained to her that police and residents are erroneously targeting them.
But Ramos said such a meeting would have to be in a "small environment," with only a few representatives of the community and the police department.
"They're not going to come to a meeting like this," she said.