With respect to flavored e-liquids, there has been considerable national media attention in recent months concerning the targeted sales of electronic smoking devices, like JUUL, to young people. Even the Food and Drug Administration has come out aggressively against flavored e-liquids, having drawn a direct connection between electronic smoking devices and increased nicotine addiction among teens. A CDC study from 2014 found that more than 250,000 youth who had never smoked a cigarette before used an electronic smoking device in 2013. In 2014, 33 percent of Baltimore high school students reported having used electronic smoking devices, according to the Maryland Youth Risk Behavior Survey that year. Nicotine is toxic, highly addictive and has negative effects on brain development in adolescence. Nicotine addiction developed through the use of electronic smoking devices also greatly increases the likelihood of cigarette and other tobacco product use.