Dante Cunningham had 15 points for the Wildcats (20-4, 8-3) and Shane Clark had 16. The host Wildcats knocked off their third Top 25 team in their six-game winning streak and won their 26th straight game at the Pavilion.
They reached the 100-point mark in consecutive Big East games for the first time in team history.
Marquette (20-4, 9-2) was unranked when it came away with a home victory against Villanova in the conference opener, a win that sparked the Golden Eagles to a 9-0 start in the Big East. Now, they've lost two straight on the road.
No. 9 Michigan State 54, Michigan 42: : Freshman Delvon Roe scored 11 of his season-high 14 points in the first half and Kalin Lucas had 13 of his 15 points after halftime, leading the visiting Spartans (20-4, 10-2 Big Ten) to their third straight win. They have won 16 of 19 in the series.
The Wolverines (15-10, 5-7), who trailed by eight at halftime and 12 early in the second half, pulled within four with 4:48 left but couldn't get closer.
No. 25 Florida State 68, Virginia 57: : Toney Douglas scored 19 points and matched a career high with seven assists as the host Seminoles (19-5, 6-3) handed the Cavaliers (7-13, 1-8) their eighth consecutive loss.
Douglas, the ACC's leading scorer in conference competition, scored 15 points in a decisive second half - including successive three-point shots 25 seconds apart that gave Florida State a 40-35 lead.
BOWIE STATE 84, VIRGINIA STATE 50:: The Bulldogs (12-11, 9-7 Central Intercollegiate Athletic Association) shot 61.5 percent in the second half to put away the visiting Trojans (10-15, 5-10).
BOWIE STATE 64, VIRGINIA STATE 53:: The Lady Bulldogs (14-9, 13-3 CIAA) maintained their lead in the CIAA's eastern division by beating the visiting Trojanettes (19-5, 10-5).
Bowie State's Bianca Lee led all scorers with 21 points.
JOHNS HOPKINS 64, GETTYSBURG 45:: The Blue Jays (12-10, 10-5 Centennial) held the host Bullets (12-10, 9-6) to 25 percent shooting to earn the victory and move into second place in the conference.
ALVERNIA 74, WASHINGTON COLLEGE 62:: The Shorewomen (10-11) opened the game with a 20-6 run but fell to the host Crusaders (14-7).
MCDANIEL 79, DICKINSON 56:: Kim Staub had a game-high 14 points to lead the Green Terror (12-9, 10-6 Centennial) over the visiting Red Devils (12-10, 9-6).
Off the court
Central Michigan: : A former player is suing the school and its women's coach, claiming her heterosexuality was a factor in losing a scholarship after two seasons.
Brooke Heike said she fell out of favor with Sue Guevara immediately after the coach was hired in 2007; she lost her scholarship after the 2007-08 season.
Heike said Guevara told her she wore too much makeup and was not the coach's "type." That meant she wasn't a lesbian, according to a lawsuit filed last week in federal court in Bay City. "I didn't feel that she did anything to improve herself after being told over and over what she needed to do," Guevara told an appeals committee last June.
Central Michigan spokesman Steve Smith said the allegations have no merit, and the university will "vigorously defend its position in court."
Heike has been attending community college since leaving campus, her lawyer, Cindy Rhodes Victor, said.
"She was so traumatized by the experience," Victor said yesterday.
The lawsuit seeks a jury trial and a cash award.