Roy made 10 steals, and Oden grabbed 14 rebounds, including nine on the offensive end.
Antawn Jamison scored 19 points, and Juan Dixon (Maryland, Calvert Hall) added 13 for Washington (9-34), which lost for the ninth time in its past 11 games.
Excluding Dixon, the Wizards' bench contributed just 11 points.
Mo Williams added 25 points for the Cavs (34-8).
Deron Williams had a season-high 16 assists and scored 17 points for the Jazz (25-19), which had won seven straight at home.
Brand, who missed 16 games after dislocating his right shoulder Dec. 17, had six points in 13 minutes off the bench.
The Sixers (21-21) won for the eighth time in nine games.
Udonis Haslem added 12 points - including two huge baskets down the stretch - for the Heat, which finished with four turnovers, an all-time franchise low, and dealt the Magic its second straight loss.
Dwight Howard had 22 points and 10 rebounds for Orlando before he was ejected with 1.1 seconds left.
O.J. Mayo scored 23 points to lead the Grizzlies.
Memphis played its second game under interim coach Johnny Davis. The Grizzlies are scheduled to introduce new coach Lionel Hollins, a Bucks assistant, at a news conference today.
The Kings' Brad Miller, who finished with 14 points, 13 rebounds and nine assists, saw his jumper bounce off the back of the rim at the buzzer that would have sent the game into overtime.