Hasheem Thabeet added 15 points, 17 rebounds and four blocked shots for UConn (16-1, 5-1 Big East). Jeff Adrien had 13 points and 12 rebounds, the senior's 40th career double double.
UConn has won 22 of its past 24 games against Seton Hall (9-8, 0-5).
The Explorers (9-7, 1-2) were coming off a 68-61 win over Charlotte on Wednesday.
Northwestern 74, No. 18 Minnesota 65: : Craig Moore hit six three-pointers and scored 22 to lead the Wildcats (9-6, 1-4 Big Ten) to their first win over a ranked opponent in nearly three years.
Lawrence Westbrook scored 18 for Minnesota (16-2, 4-2).
David Palmer led Iowa with 19 points for the Hawkeyes (11-7, 1-4), who lost their third straight.
D.J. Kennedy had 18 points for St. John's (10-7, 1-4).
Top 25 women
No. 3 Oklahoma 71, No. 8 Texas A&M; 59: : Danielle Robinson had 19 points and 10 assists and two other Sooners added double doubles as host Oklahoma (13-2, 3-0 Big 12) won its ninth straight overall and its second straight over a ranked conference foe.
Texas A&M; (14-2, 2-1) had been off to the best start in school history. Takia Starks scored 19 points, and Danielle Gant added 18 for the Aggies.
No. 11 California 57, No. 9 Stanford 54: : Alexis Gray-Lawson scored a career-high 37 points, converting two free throws with 1:09 to play that put the Golden Bears (14-2, 5-0 Pacific-10) ahead for good and ending the Cardinal's five-game winning streak.
Jayne Appel had 18 points, eight rebounds and four assists playing all game in foul trouble for the Cardinal (13-4, 4-1).
Florida State 59, No. 24 Georgia Tech 49: : Jacinta Monroe had 15 points, 10 rebounds and a school-record nine blocks to help the host Seminoles (16-4,. 4-0 ACC) extend their winning streak to seven games. Alex Montgomery led the Yellow Jackets (13-4, 1-2) with 14 points and Jacqua Williams added 12.
Towson 63, North Carolina-Wilmington 54: : A 15-2 run early in the second half allowed the Tigers (10-5, 2-3 Colonial Athletic Association) to turn a six-point deficit into a seven-point lead against the Seahawks (7-9, 1-4).
Towson had four players score in double figures, led by a career-high 16 points by Haliena Snowden (Seton Keough).
Saint Peter's 76, Loyola 52: : The visiting Greyhounds (8-9, 3-4 Metro Atlantic Athletic Conference) committed 28 turnovers in the loss to the Peahens (5-11, 2-5). Meredith Tolley had 12 points for Loyola.
Off the court
Connecticut: : Freshman guard Caroline Doty, who tore the anterior cruciate ligament in her left knee in Saturday's win over Syracuse, will miss the rest of the season, the school announced yesterday.