The Tigers (6-8, 1-1 Colonial Athletic Association) had trailed the Dukes (8-6, 0-2), who won four of their previous five games, most of the night. However, Towson turned up the defensive pressure and Hairston's free throws gave the Tigers their first lead since 15-13 with nine minutes remaining in the first half.
With 25 seconds left, a steal by Hairston gave the Tigers the ball. Robert Nwankwo was fouled with 21 seconds left, but he missed both free throws.
Devon Moore was double-teamed in front of James Madison's bench, and the Dukes called timeout with four seconds left. After the timeout, Andrey Semenov's long three-point attempt missed, and Towson held on for the win.
"It wasn't the 'Mona Lisa,' but we'll take it," Towson coach Pat Kennedy said. "This was a huge win for us. We've been on the road for weeks, and it feels great to come home and pull out a tough win. In the final minutes, they had some trouble with our 1-3-1 extended defense, and they couldn't get the open looks they wanted. Our guys played tremendous defense down the stretch."
After the Dukes took a 54-51 lead on a basket by Juwann James with 5:18 remaining, they were held without a field goal the rest of the way. On its final seven possessions, James Madison had three turnovers, made three of six free throws and missed a long three-point try.
Rocky Coleman added 12 points for Towson, and Jarrel Smith and Troy Franklin each scored 10.
James scored a career-high 24 points before fouling out for the Dukes. James' previous career high was 23 points, which he accomplished twice against Towson.
Brett Harvey added 22 points to help Loyola (5-9, 1-2 Metro Atlantic Athletic Conference) end a two-game losing streak.
Julius Coles led Canisius (5-8, 0-3) with 15 points.
Barney, a 6-foot-3 guard playing his first season for the Greyhounds after sitting out last season after a transfer from Providence, scored 20 of his 41 points in the first half, going 7-for-9 from the field. The Greyhounds, also taking advantage of 10 Canisius turnovers, took a 36-29 lead at halftime.
Loyola opened the second half with an 13-3 run for a 17-point lead.
The Greyhounds shot 47.5 percent (29-for-61) for the game, while Canisius was 22-for-52.
Barney, a two-time first-team Sun All-Metro player who came into the game yesterday averaging 14.3 points, was 3-for-4 from three-point range and hit eight of nine from the foul line.
The junior guard scored 15 of his team-high 20 points in the opening half, helping Oklahoma (13-1) roll. Four days earlier at Arkansas, the Sooners lost for the first time when they fell behind 21-8 early and trailed by 25 before mounting a frantic comeback.
Although Coppin State (2-11) did not figure to present a challenge for Oklahoma, Sooners coach Jeff Capel was adamant about his team opening the game with more energy.
"We definitely wanted to get off to a good start - play with a sense of urgency. I thought we did that today," said Capel, whose team opened with an 11-2 run and never trailed.
The Eagles were led by Tywain McKee with 20 points. Despite also getting 16 points from Brian Chesnut and 13 from Michael Harper, Coppin State shot just 36 percent from the field.
The Eagles used a 10-4 run to cut their deficit to 38-23 with just more than three minutes left in the first half, but that's as close as they would get. The Sooners closed the half on a 7-0 run and dominated the rest of the way, leading by 33 in the second half.
NEBRASKA 88, UMES 56: : Ade Dagunduro scored 18 points and the host Cornhuskers (9-3) opened the second half with a 13-4 run to put away the Hawks (1-8).
Nebraska enjoyed a season high in points, hitting 61 percent of its shots.
UMES was the 12th Cornhuskers opponent to be held to 66 points or fewer this season. The Hawks hit just 41 percent of their shots.
The Huskers' defense forced 16 turnovers, 12 of them steals. Those turnovers led to 23 points.
Nebraska led 40-28 at the half and put the game out of reach with a 13-4 spurt opening the second, capped by Brandon Richardson's three-pointer from the corner that made the score 53-32 with 14:47 remaining.
Whitney Cunningham (14 points) made four free throws and Sesalie Johnson hit a layup for a 53-50 Coppin advantage. Hawkins, who finished with 14 points, made the deciding shot with 1:10 left.
Corin Adams had 21 points for the Bears.
KENT STATE 77, UMES 47: : The host Golden Flashes (11-1) - paced by Jena Stutzman with 20 points - led by 33 points en route to the victory.
Casey Morton scored 15 points and April McBride had 11 for the Hawks (2-7).
WIDENER 74, MCDANIEL 54: : Ali Moreland and Whitney Snoops each scored 11 points in a losing effort for the visiting Green Terror (4-4).
Becky Tyler had 20 points for the Pioneers (8-4).