"Being named as the fourth head coach in Towson football history is a tremendous honor for me," Ambrose said in a statement. "All three of my predecessors are legends and men that I admire. It's with great humility that I follow in their footsteps. I am so thankful to be part of this program's past, and I am grateful to be part of the future. I can't wait to come back home and get started."
Ambrose, a quarterback and wide receiver, played for Towson's second coach, Phil Albert, and served as an assistant under Combs. (Carl Runk was the Tigers' first head coach.)
Ambrose began his coaching career while still a student at what was then Towson State. After suffering a knee injury that kept him from playing as a senior, he joined Combs' staff as a student assistant in 1992. While continuing as an assistant coach for the Tigers, Ambrose was promoted to offensive coordinator in 1998 and associate head coach in 2000.
"Rob was on our list from the very beginning," Towson athletic director Mike Hermann said in a statement. "But I felt it was important to conduct a thorough national search to ensure that we found the very best coach for Towson University. We had an outstanding field and discussed this opportunity with many well-respected coaches. At the end, it became clear that Rob Ambrose was the best choice to lead our program. Not only is he ready and willing to be the head coach of a college football program, he's ready and willing to do the job at Towson."
Ambrose was head coach for a year at Catholic in 2001, posting a 3-7 record, before moving on to Connecticut. The Huskies have gone 48-36 during his time on their staff.
As quarterbacks coach for UConn, he worked with Dan Orlovsky, now the starter for the Detroit Lions.
"It's awesome that Rob Ambrose is the new coach at Towson," Orlovsky said in a statement. "He's been an unbelievable coach for me, and he's been a great friend. I will always remember the things he taught me that helped me grow as a quarterback and as a person. Some of the things that he taught me are laminated and hanging in my locker.
"One of the best things he has done is challenge me to get better - and he does it in the right way. Rob is going to be a great addition to the Towson staff, and he will do a great job."