Chas McFarland had 14 points for the Demon Deacons (11-0), off to their best start since winning the first 11 games of 2003-04. Wake Forest led by four points at halftime before roaring out of the break.
The Demon Deacons opened the second half with a 15-3 run that pushed the margin to double digits, then spent the rest of the game steadily increasing the lead while putting on a show of the full-court athleticism that has made them one of the favorites in the Atlantic Coast Conference.
The Pirates (8-3) were outscored 54-17 after halftime.
No. 4 Oklahoma 70, Rice 58: : Freshman Willie Warren scored a career-high 31 points, Blake Griffin added 27 points and 11 rebounds, and the visiting Sooners (12-0) overcame turnovers and bad shooting to beat the Owls (4-7).
Notre Dame (9-2) led 37-21 at halftime despite shooting 34 percent. Harangody shot 5-for-14 (36 percent) from the field but was 13-for-14 from the free-throw line.
No. 15 Ohio State 83, UNC-Asheville 59:: Freshman B.J. Mullens, getting the most playing time of his brief career, scored 19 points to lead the host Buckeyes (9-0) past the Bulldogs (4-8).
No. 21 Baylor 74, Hartford 59: : Curtis Jerrells had 17 points, 11 rebounds and 10 assists for the Bears' first triple double since Brian Skinner of the Los Angeles Clippers had one on Nov. 29, 1997, and host Baylor (10-1) defeated the Hawks (4-8).
No. 24 Michigan 76, Florida-Gulf Coast 59: : DeShawn Sims had 20 points and a career-high 20 rebounds to lead the host Wolverines (9-2) past the Eagles (4-8) for their fourth straight victory.
No. 21 Oklahoma State 90, Eastern Kentucky 35: : Andrea Riley scored 23 points and the host Cowgirls (8-2) routed the Lady Colonels (3-6).
Off the court
Men's poll: : Minnesota (10-0) moved into the Associated Press' poll at No. 23, its first appearance in the rankings since December 2002.
Also moving into the poll for the first time this season were No. 24 Michigan (8-2) - last ranked in February 2006 - and No. 25 Missouri (9-1), returning to the poll for the first time since December 2003.
North Carolina (11-0) was again a unanimous No. 1, as it has been since the preseason poll.
Women's poll: : Maryland moved up a spot to No. 14 in the AP poll.
South Dakota State (12-1) joined the poll for the first time, entering at No. 25.
Connecticut remained a unanimous No. 1 for the fourth straight week. This is the 113th time in school history the Huskies have been the top team in the poll, matching Tennessee as the all-time leader.