Broncos (2-1) @ Colts (3-0) -- The RCA Dome has been a house of horrors for the Broncos. Denver's new defensive coordinator, Jim Bates, gets his chance to stop Peyton Manning indoors.

Chiefs (1-2) @ Chargers (1-2) -- A tough early-season schedule has the Chargers squabbling. The schedule gets better, but they can't afford a 1-3 start.