WEEK 1
SAINTS@COLTS
Tonight's game kicks off the season and is what the Super Bowl matchup should have been last February -- an offensive feast with quarterbacks Drew Brees and Peyton Manning.
WEEK 2
CHARGERS@PATRIOTS
LaDainian Tomlinson didn't like how the Patriots celebrated their playoff win last season. Now he gets to make his statement.
WEEK 3
TITANS@SAINTS
Two of the league's budding stars clash when Vince Young's Titans meet Reggie Bush's Saints. They were the two best offensive players in the 2006 draft.
WEEK 4
PATRIOTS@BENGALS
The Patriots' defense was ravaged by the Colts in the AFC championship game. Now it faces the best imitation of the Colts' no-huddle passing game in Carson Palmer's crew.
WEEK 5
CHARGERS@BRONCOS
Norv Turner has to take the Chargers further than Marty Schottenheimer did. The road passes through Denver, where the Broncos have reloaded.
WEEK 6
SAINTS@SEAHAWKS
In a battle for NFC supremacy, the Saints and Seahawks will be thinking about playoff tiebreakers and home-field advantage, even though it's early.
WEEK 7
RAVENS@BILLS
How will Buffalo welcome back Willis McGahee? How will he respond? It's the subplot that will draw the most attention.
WEEK 8
STEELERS@BENGALS
The Mike Tomlin era in Pittsburgh will be well under way by late October, but it will get an acid test against division foe Cincinnati.
WEEK 9
PATRIOTS@COLTS
In January, Patriots defenders wilted in the RCA Dome heat, lost to the Colts and missed the Super Bowl. Bill Belichick hasn't forgotten.
WEEK 10
COLTS@CHARGERS
A week after playing the Patriots, the Colts have to face Tomlinson with their rebuilt defense. Advantage, Tomlinson.
WEEK 11
BEARS@SEAHAWKS
Another game that could determine the postseason seeding in the NFC. If Bears QB Rex Grossman has made it this far, he must be doing OK.
WEEK 12
RAVENS@CHARGERS
Brian Billick will have to be at his best to navigate the Ravens through a three-week, playoff-like stretch, starting in San Diego.
WEEK 13
PATRIOTS@RAVENS
Adalius Thomas returns to Baltimore with the Patriots, but the Ravens still might have the better defense. They'll need it against Tom Brady.
WEEK 14
COLTS@RAVENS
One more chance for a statement game for the Ravens. They let the playoff game against the Colts get away last season; they won't want to let it happen twice.
WEEK 15
JETS@PATRIOTS
This game might determine the AFC East title. Jets coach Eric Mangini more than held his own against his mentor last season.
WEEK 16
EAGLES@SAINTS
The top seed in the NFC could be at stake here. If Donovan McNabb is healthy, the Eagles may be the favorites.
WEEK 17
COWBOYS@REDSKINS
The Cowboys could be pushing for a playoff spot. Unless Joe Gibbs turns things around, the Redskins could be pushing him out the door.