Dr. Nasser Javadpour, head of the urology department at Maryland General Hospital and an expert on testicular cancer, died of cancer Oct. 26 at Johns Hopkins Hospital. He was 56.
Dr. Javadpour, who developed a substitute bladder for cancer patients, maintained homes in Baltimore and in Daytona Beach, Fla.
He was a professor of medicine at the University of Maryland medical school from 1985 until 1991 when he left to head the Division of Urology at Maryland General.
It was while he was associated with the University of Maryland Hospital and Medical School as a urologic oncologist that he discovered the biological marker for testicular seminoma.
"By finding this marker, known as placenta alkaline phosphates," he said in a 1985 interview, "we are able to detect this disease earlier, forecast relapses earlier, make the therapy more precise and increase survival. We have had significant results in the worst cases of seminoma tumor. The cure rate has gone from 60 percent to 90 percent.
"I believe we are going to be able to cure this disease with minimum complications and even avoid some of the invasive therapy of the past, giving these young people a better survival and a better quality of life." Testicular cancer strikes men mostly between 20 and 40. A strong advocate of self-examination, Dr. Javadpour said in an interview, "It's not that young men are reluctant to do self-examination, it's just that no one has taught them to do that. It's not as advertised as in the breast. Yet, it could be equivalent to the breast."
He developed the substitute bladder -- made from intestine and attached to the urethra -- which eliminated the need for a quarter-inch hole in the abdomen, catheter and bag. It was created for cancer patients who had lost their bladders to disease.
Born and reared in Shiraz, Iran, he received his medical degree from the American Medical School in Iran in 1962. He interned at Cook County Hospital in Chicago from 1962 to 1963 and completed his surgical residency at the University of Chicago medical school and Mount Sinai Medical Center from 1964 to 1967.
He did his urology residency at the University of Minnesota Medical Center, the university's Children's Hospital and St. Paul-Ramsey Hospitals from 1963 to 1964. From 1967 to 1969, he was an American Urological Association research scholar and visiting scientist at the Armed Forces Institute of Pathology.
Dr. Javadpour had held eight research staff appointments, received 19 grants for medical research and was active on editorial boards of six medical publications. He was a member of 20 medical societies, including the American College of Surgeons, American Association of Cancer Research, Society of University Urologists, American Urological Association and the Maryland Urological Society.
He wrote 12 books on urologic oncology and filmed and edited eight movies on testicular cancer. He was a visiting professor at more than 65 universities, including the Mayo Clinic, Brown University, Johns Hopkins Cancer Center, University of Switzerland at Bern and the University of Chicago. He also gave 230 national and international guest lectures.
A memorial service was set for noon today at the University of Maryland at Baltimore's Davidge Hall, 522 W. Lombard St., Baltimore.
He is survived by his wife, the former Kathleen Wroski, whom he married in 1963; a son, Brian Javadpour of Baltimore; and two daughters, Dana Javadpour of Dallas and Tara Javadpour of Gaithersburg.
The family suggested memorial contributions to the American Cancer Society.