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August 2002 - NIOSH scientists' findings on butter flavoring/diacetyl hazards appear in New England Journal of Medicine
October 2002 - Flavoring industry group downplays diacetyl hazard in comments to NIOSH.
December 2003 - NIOSH issues alert to be sent to 4,000 businesses that might use or make butter flavoring.
August 2004 - Flavor and Extract Manufacturing Association issues its report on precautions in use of flavorings.
December 2004 - As reports of health problems emerge in more plants, California officials seek NIOSH's help.
2005 - California officials reverse course, agreeing to let industry-paid consultant investigate workers' health. NIOSH is shut out.
February 2006 - Ohio workers' compensation agency tells NIOSH that at least 15 workers from a Cincinnati flavoring plant have respiratory disease.