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Portions of several main thoroughfares in Baltimore will close Saturday for separate events, according to the Baltimore Department of Transportation.

The Charles Street 12 run will close lanes on Charles Street Saturday morning. One lane of traffic will be closed for runners along the route, and parking will be restricted in some areas.

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The race begins in Towson at 7:30 a.m. Participants will enter the city on Charles Street at Gittings Avenue and continue through downtown Baltimore. The course turns left on Lee Street, right on Light Street and left on Key Highway, where it continues to finish in front of Under Armour’s Tide Point headquarters.

And from 5 a.m. to 7 p.m. Saturday, two lanes on Howard Street will close in Midtown-Belvedere between Preston and John streets. The road will be closed for a crane operation, and the DOT urged motorists to watch for changing traffic patterns and seek alternative routes.

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