Data based on initial fall enrollments sent to the Maryland Higher Education Commission.
| College | Total enrollment (2010) | Total enrollment (2015) | Difference |
| Coppin State | 3800 | 3108 | -18% |
| McDaniel | 3570 | 2980 | -17% |
| St. John’s College | 538 | 457 | -15% |
| Notre Dame | 2982 | 2612 | -12% |
| St. Mary’s College | 2017 | 1772 | -12% |
| Goucher | 2299 | 2141 | -7% |
| University of Baltimore | 6501 | 6229 | -4% |
| Washington College | 1470 | 1427 | -3% |
| Bowie State | 5578 | 5430 | -3% |
| UMES | 4540 | 4465 | -2% |
| Morgan State | 7805 | 7725 | -1% |
| UMB | 6349 | 6329 | 0% |
| Loyola | 6061 | 6050 | 0% |
| UMCP | 37641 | 38140 | +1% |
| Towson | 21840 | 22284 | +2% |
| Salisbury | 8397 | 8671 | +3% |
| Frostburg State | 5470 | 5756 | +5% |
| MICA | 2102 | 2215 | +5% |
| Stevenson | 3941 | 4185 | +6% |
| Mount St. Mary's | 2112 | 2257 | +7% |
| UMBC | 12888 | 13839 | +7% |
| Johns Hopkins | 20977 | 22685 | +8% |
| UMUC (U.S. only) | 39577 | 49203 | +24% |
| Total | 208,455 | 219,960 | +5.5% |