The Ritz Cabaret Gentleman's Club
This Upper Fells Point-area strip club was essentially its own character in Season One. The Ritz doubled as Orlando's, headquarters for crime boss Avon Barksdale.
The Red Star
This punk/metal club doubled as Kavanaugh's, where the Irish wakes were held for various dead and retiring officers.
The Brewer's Art
This Mount Vernon brewpub seemed an unlikely candidate for a "Wire" bar. In the basement, up-and-coming crime boss Marlo Stanfield meets Devonne, who would later betray him, for the first time.
While you're in Mount Vernon, stop by this watering hole and drink like the Sun reporters in season five. Do a shot if you catch a City Paper reporter at the bar.
The Prime Rib
One of the oldest gay bars in the city—it opened more than a half-century ago—Leon's was location for the scene where a very uncomfortable henchman seeks out bandit Omar Little, who is gay.