The Triple-A Norfolk Tides lost to the Syracuse Chiefs, and the Single-A Frederick Keys were beaten by the Potomac Nationals.
The Single-A Delmarva Shorebirds swept a doubleheader from the Greensboro Grasshoppers, and the short-season Single-A Aberdeen IronBirds edged the Staten Island Yankees in extra innings.
The Rookie-level GCL Orioles fell to the GCL Twins.
The Double-A Bowie Baysox and Rookie-level Bluefield Orioles were idle.
Earlier today, there were several roster moves in the Orioles' minor league system.
Starting pitcher Pedro Beato was promoted from Frederick to the Baysox.
Relief pitcher Brandon Cooney joined the Keys from Delmarva, and starting pitcher Kenny Moreland returns to Frederick from the IronBirds.
Infielder Buck Britton was transferred from the Keys to Aberdeen, and relief pitcher Mick Mattaliano headed to the Shorebirds from the IronBirds.
Score: Syracuse Chiefs 8, Norfolk Tides 2 (Box score)
Recap: First baseman Brandon Snyder was 3-for-4 with an RBI in the Tides' 8-2 loss to Syracuse at Harbor Park.
Norfolk third baseman Brandon Pinckney contributed two hits and a run scored, and center fielder Joey Gathright was 1-for-3 with a walk.
Tides starting pitcher Jake Arrieta (3-5) allowed four runs and eight hits in five innings. The 23-year-old right-hander struck out four batters and issued two walks.
Orioles relief pitcher Dennis Sarfate retired all three batters he faced in his latest injury rehabilitation assignment for the Tides.Frederick Keys (A)
Score: Potomac Nationals 5, Frederick Keys 3 (Box score)
Recap: First baseman Robbie Widlansky collected a pair of doubles and a single in the Keys' 5-3 loss to Potomac at Harry Grove Stadium.
Frederick third baseman Brandon Waring was 2-for-4 with a double and a walk, while right fielder Matthew Tucker contributed two hits and a run scored.
Keys starting pitcher Nathan Nery (3-5) gave up five runs and nine hits in 5 1/3 innings. The 23-year-old left-hander struck out two batters and didn't walk anyone.
Center fielder Matt Angle hit a double and scored two runs for the Keys.
Game 1 score: Delmarva Shorebirds 4, Greensboro Grasshoppers 2, 7 innings (Box score)
Game 1 recap: The Shorebirds managed only two hits in the first game of the doubleheader, but they beat Greensboro, 4-2, at Arthur W. Perdue Stadium.
Delmarva catcher Luis Bernardo hit a three-run double in the fourth inning, and shortstop Rodolfo Cardona picked up an RBI on a bases-loaded walk.
Starting pitcher Ryan O'Shea gave up two runs and six hits in four innings for the Shorebirds, but he didn't factor in the decision. The 23-year-old right-hander struck out four batters and issued two walks.
Shorebirds relief pitcher Shane Mathews (1-3) retired all six batters he faced to earn the victory, and closer Cliff Flagello tossed one scoreless inning to pick up his third save of the season.
Right fielder Ronnie Welty collected the Shorebirds' other hit.
Game 2 score: Delmarva Shorebirds 3, Greensboro Grasshoppers 1, 7 innings (Box score)
Game 2 recap: First baseman Joe Mahoney was 2-for-3 with an RBI, a stolen base and a run scored in the Shorebirds' 3-1 win over Greensboro during the nightcap.
Welty added a double and an RBI for Delmarva, and second baseman L.J. Hoes contributed a single and an RBI.
Shorebirds starting pitcher Oliver Drake (7-6) allowed one run and four hits in 6 1/3 innings. The 22-year-old right-hander collected seven strikeouts and walked one batter.
Delmarva relief pitcher Brett Bordes recorded the final two outs of the game to pick up his second save of the season.
Score: Aberdeen IronBirds 1, Staten Island Yankees 0, 10 innings (Box score)
Recap: Second baseman Tyler Kelly hit a sacrifice fly in the bottom of the 10th inning to lift the IronBirds to a 1-0 victory over Staten Island at Ripken Stadium.
Aberdeen catcher Brian Ward was 2-for-4, and left fielder Richard D'Oleo added a triple.
IronBirds starting pitcher Tyler Sexton tossed seven scoreless innings. The 24-year-old left-hander collected eight strikeouts, allowed four hits and hit a batter.
Relief pitcher Jose Barajas (3-2) earned the win for Aberdeen after retiring all three batters he faced.
Score: GCL Twins 3, GCL Orioles 2 (Box score)
Recap: Catcher Dennis Perez was 2-for-3 with a double and a walk in the Orioles' 3-2 loss to the Twins.
Orioles second baseman Anderson Childers added two hits, including a double, and designated hitter Tyler Stampone picked up an RBI.
Starting pitcher Zachary Petersime allowed two runs, four hits and three walks in four innings for the Orioles, and relief pitcher Dustin Carder (2-1) suffered the loss after giving up one unearned run and two hits in four innings.