The Triple-A Norfolk Tides lost to the Gwinnett Braves, and the Double-A Bowie Baysox were beaten by the Akron Aeros.
The Single-A Frederick Keys were swept in a doubleheader by the Wilmington Blue Rocks.
The Rookie-level Bluefield Orioles topped the Bristol Sox, and the Rookie-level GCL Orioles were edged by the GCL Twins in extra innings.
The Single-A Delmarva Shorebirds were idle, and three players from the short-season Single-A Aberdeen IronBirds participated in the New York-Penn League All-Star Game.
In addition to the earlier roster moves, the Keys also activated right-hander Chorye Spoone from the disabled list. To make room on the roster, Frederick placed left-hander Nathan Nery on the disabled list, retroactive to Aug. 16.
Recap: Third baseman Josh Bell was 2-for-4 with a two-run home run, but the Baysox were pounded, 12-3, by Akron.
Bowie starting pitcher Brandon Erbe gave up two runs (one earned), three hits and three walks in four innings, and relief pitcher Jim Hoey (2-5) allowed four runs (three earned) and four hits in one inning.
Baysox left fielder Jonathan Tucker was 2-for-4 with a double and a run scored, and designated hitter Paco Figueroa added two hits and a stolen base.
Frederick Keys (A)
Game 1 score: Wilmington Blue Rocks 6, Frederick Keys 5, 7 innings (Box score)
Game 1 recap: Shortstop Pedro Florimon Jr. was 2-for-3 with a double, three RBIs and a run scored as the Keys were edged by Wilmington, 6-5, in the first game of the doubleheader at Harry Grove Stadium.
Catcher Dennis Perez was 1-for-3 with an RBI for the Orioles.
Orioles relief pitcher Chris Hervey (1-1) allowed one run, one hit, one walk and he hit a batter in two-thirds of an inning.
New York-Penn League All-Star Game
Score: American League All-Stars 4, National League All-Stars 2 (Box score)
Recap: IronBirds relief pitcher Jacob Smith earned the win for the American League All-Stars in a 4-2 victory over the National League All-Stars in State College, Pa., after tossing one scoreless inning.
Aberdeen infielder Tyler Kelly was 1-for-3 with a double and a run scored, and infielder Levi Carolus was 0-for-1.
Staten Island Yankees second baseman Jimmy Paredes was named as the game's Most Valuable Player after going 1-for-2 with a two-run home run in the seventh inning.