The Triple-A Norfolk Tides lost to the Gwinnett Braves, while the Double-A Bowie Baysox topped the Harrisburg Senators on the road.
The Single-A Frederick Keys dropped a decision to the Salem Red Sox, and the Single-A Delmarva Shorebirds beat the Greenville Drive.
The short-season Single-A Aberdeen IronBirds were blanked by the Mahoning Valley Scrappers.
The Rookie-level Bluefield Orioles won against the Greeneville Astros in extra innings, and the Rookie-level GCL Orioles fell to the GCL Red Sox.
Score: Gwinnett Braves 8, Norfolk Tides 2 (Box score)
Recap: Center fielder Jeff Fiorentino was 2-for-4 with a solo home run in the fourth inning, but the Tides fell, 8-2, to Gwinnett.
Norfolk starting pitcher Chris Waters (8-4) gave up five runs and eight hits in 4 1/3 innings. The 28-year-old left-hander walked three batters, threw a wild pitch and collected two strikeouts.
Tides third baseman Brandon Pinckney contributed a double and a run scored, and catcher Robby Hammock was 1-for-2 with a walk.
Relief pitcher Alberto Castillo allowed two runs and three hits in one inning for the Tides.Bowie Baysox (AA)
Score: Bowie Baysox 7, Harrisburg Senators 1 (Box score)
Recap: Starting pitcher Radhames Liz (4-1) tossed seven scoreless innings, and the Baysox cruised past Harrisburg, 7-1. The 25-year-old right hander struck out eight batters and allowed four hits.
Bowie second baseman Miguel Abreu was 3-for-5 with three RBIs and a run scored, while left fielder Jonathan Tucker collected a single, two stolen bases and two runs scored.
Designated hitter Kraig Binick added two hits, an RBI and a run scored in his Double-A debut for the Baysox, and shortstop Robert Valido was 2-for-5 with a run scored.
Former Orioles utility player Freddie Bynum committed three errors while playing shortstop for Harrisburg in tonight's game. Bynum was also caught stealing once.
Score: Salem Red Sox 8, Frederick Keys 5 (Box score)
Recap: The Keys scored four runs in the top of the first inning, but they were unable to hold the early lead in an 8-5 loss to Salem.
Frederick shortstop Pedro Florimon Jr. hit a solo home run, walked twice and scored two runs, and left fielder Tyler Henson was 2-for-4 with two RBIs and a run scored.
In 23 games since the Carolina League All-Star break, Henson is batting .354 with two home runs and 14 RBIs. The 21-year-old utility player also has five doubles, two triples, 16 runs scored and four stolen bases during that span.
Starting pitcher Rick Zagone allowed five runs and six hits in four innings for the Keys, but he didn't factor in the decision. Frederick relief pitcher Jake Stevens (3-5) suffered the loss after giving up three runs (two earned), two hits and three walks in two innings.
Keys catcher Caleb Joseph was 3-for-5 with a run scored, while second baseman Ryan Adams and third baseman Matt Tucker each added an RBI.
Score: Delmarva Shorebirds 3, Greenville Drive 1 (Box score)
Recap: Right fielder Ronnie Welty hit a two-run home run in the third inning, his eighth of the season, and the Shorebirds held on for a 3-1 win over Greenville.
Delmarva first baseman Joe Mahoney added a solo shot in the second, and shortstop Greg Miclat was 1-for-3 with a walk, a stolen base and a run scored.
Shorebirds starting pitcher Oliver Drake (6-6) only gave up three hits in six scoreless innings. The 22-year-old right-hander struck out seven batters and issued two walks.
Relief pitcher Cliff Flagello tossed 2 2/3 scoreless innings to pick up his second save of the season for the Shorebirds.
Score: Mahoning Valley Scrappers 10, Aberdeen IronBirds 0 (Box score)
Recap: Starting pitcher Colin Allen (0-4) gave up four runs (one earned) and five hits in four innings, and the IronBirds were pounded, 10-0, by Mahoning Valley at Ripken Stadium.
Aberdeen shortstop Michael Mooney was 2-for-4, but he committed a throwing error. Left fielder Arthur Bonevacia was 1-for-2 after pinch-hitting for Richard D'Oleo in the sixth inning.
IronBirds relief pitcher Jake Cowan, who was the Orioles' 10th-round selection in this year's MLB draft, allowed four runs, three hits and three walks in two-thirds of an inning.
Score: Bluefield Orioles 4, Greeneville Astros 3, 10 innings (Box score)
Recap: Shortstop Gary Helmick was 3-for-4 with two doubles and three runs scored in the Orioles' 4-3 win over Greeneville in 10 innings.
Bluefield starting pitcher Bobby Bundy gave up three runs and five hits in 5 1/3 innings. The 19-year-old right-hander walked two batters and allowed a solo home run to Greeneville shortstop Jiovanni Mier, the Astros' first-round choice in this year's draft.
Third baseman Corey Thomas and catcher Dashenko Ricardo each collected a double for Bluefield, while first baseman Mike Flacco was 1-for-4 with an RBI and a run scored.
Orioles relief pitcher Sam Taveras (2-0) retired all three batters he faced, including two by strikeout, to pick up the victory.
Score: GCL Red Sox 15, GCL Orioles 3 (Box score)
Recap: Starting pitcher Chorye Spoone (0-1) allowed four runs, three hits and one walk in one-third of an inning during an injury rehabilitation assignment, and the Orioles lost, 15-3, to the Red Sox.
Orioles catcher Dennis Perez and right fielder Grolmann Gonzalez each collected two hits and a run scored, while shortstop Moises Ciriaco was 1-for-3 with a run scored.
Designated hitter Paco Figueroa added a double and an RBI in an injury rehabilitation assignment for the Orioles before being removed in the seventh inning.