The Triple-A Norfolk Tides travel to play the Charlotte Knights, while the Double-A Bowie Baysox return to Prince George's Stadium to face the Harrisburg Senators.
The Single-A Frederick Keys continue their road trip against the Kinston Indians, and the Single-A Delmarva Shorebirds meet the Kannapolis Intimidators.
The short-season Single-A Aberdeen IronBirds play against the Brooklyn Cyclones.
I'll be heading to Bowie to provide live game updates as Brian Matusz pitches for the Baysox, so be sure to check O's on Deck later tonight.
Earlier today, the Orioles announced that the injury rehabilitation assignment for shortstop Blake Davis with the IronBirds ended, and he returned to the Tides.
The Baysox also announced several rosters moves from the past two days.
Yesterday, Bowie relief pitcher Wilfrido Perez was placed on the disabled list, retroactive to July 5. It's his second trip to the DL so far this season. Perez is 2-0 with a 1.37 ERA in 24 appearances for the Baysox this year.
Today, relief pitcher Josh Perrault was promoted to Norfolk from the Baysox, and infielder Brandon Pinckney heads back to Bowie from the Tides.
Starting pitcher Zach Clark, who was on an injury rehabilitation assignment with the GCL Orioles, was activated from the disabled list. He rejoins the Baysox after making 10 starts for the team last season.
Finally, Orioles shortstop Cesar Izturis joins the Baysox for an injury rehabilitation assignment beginning tonight.
at Charlotte Knights (7:15 p.m.)
Norfolk: Jake Arrieta (1-2, 2.92 ERA)
Charlotte: Jeffrey Marquez (1-6, 9.09 ERA)Bowie Baysox (AA)
Harrisburg Senators (7:05 p.m.)
Bowie: Brian Matusz (3-0, 0.49 ERA)
Harrisburg: Matt Chico (0-1, 3.86 ERA)
Record: (4-6 in second half, 35-44 overall)
at Kinston Indians (7 p.m.)
Frederick: Pedro Beato (4-5, 4.80 ERA)
Kinston: Mike McGuire (0-0, 4.50 ERA)
Record: (6-6 in second half, 42-39 overall)
at Kannapolis Intimidators (7:05 p.m.)
Delmarva: Cole McCurry (3-6, 3.42 ERA)
Kannapolis: Charles Leesman (6-4, 2.78 ERA)
at Brooklyn Cyclones (7 p.m.)
Aberdeen: Patrick Kantakevich (0-1, 6.10 ERA)
Brooklyn: Mark Cohoon (3-0, 1.35 ERA)