The Triple-A Norfolk Tides return home to Harbor Park to face the Indianapolis Indians, and the Double-A Bowie Baysox continue their series against the Connecticut Defenders at Prince George's Stadium.
The Single-A Frederick Keys host the Salem Red Sox, and the Single-A Delmarva Shorebirds meet the Asheville Tourists.
The short-season Single-A Aberdeen IronBirds conclude their road trip against the Brooklyn Cyclones, and the Rookie-level Bluefield Orioles take on the Princeton Rays at Bowen Field.
Orioles first-round draft pick Matt Hobgood is scheduled to pitch for Bluefield.
Indianapolis Indians (7:15 p.m.)
Norfolk: Chris Waters (8-4, 4.55 ERA)
Connecticut Defenders (7:05 p.m.)
Bowie: Radhames Liz (4-1, 2.05 ERA)
Connecticut: Madison Bumgarner (7-1, 1.56 ERA)
Record: (15-15 in second half, 46-53 overall)
Salem Red Sox (7 p.m.)
Frederick: Rick Zagone (0-2, 5.88 ERA)
Salem: Stephen Fife (1-0, 1.54 ERA)
Record: (16-14 in second half, 52-47 overall)
at Asheville Tourists (7:05 p.m.)
Delmarva: Chris Salberg (2-1, 4.50 ERA)
Asheville: Jonnathan Aristil (1-6, 4.97 ERA)
at Brooklyn Cyclones (7 p.m.)
Princeton Rays (7 p.m.)
Bluefield: Matt Hobgood (0-0, 6.00 ERA)