Brandon Jacobs, RB (NYG): Jacobs is an upright runner and is a 10-game season waiting to happen. Well, now it's happened. Jacobs, in his first day as the full-time Giants running back, sprained his MCL and is out 3-5 weeks. Somewhere, Tiki Barber is smiling. With Manning also out, backup Derrick Ward doesn't have much value. This offense will not be able to move the ball until Manning comes back.