"House"-hold name: Mos Def as Lee.
"House"-lights: House has a motorcycle accident and ends up in a New York hospital where Lee is suffering from locked-in syndrome after suffering a bicycle accident. The doctors think Lee is braindead and want to harvest his organs, but House notices eye movement and puts himself on the case. The team eventually finds out that the man got a bacterial infection from rats where he worked as a janitor, but the actual interesting part is watching him communicate with the team via a brain-computer interface, since all forms of other communication are out of the question.
Out-"House": Mos Def is a successful hip-hop artist who received great critical acclaim for his turn on "House." He also starred in "The Italian Job" and the HBO movie "Something the Lord Made."