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"House"-hold name: Joshua Malina as Tucker.
"House"-lights: Tucker is a former oncology patient of Wilson's, who is now suffering a brain tumor that was caused by the treatment for his leukemia five years ago. Wilson prescribes a double dose of chemo, which zaps the cancer but damages Tucker's liver so severely that he has about a day to live. After seeing Tucker reunite with his estranged wife and daughter on his deathbed, Wilson donates a piece of his own liver to save Tucker. Who promptly throws his wife over to go back to a girlfriend roughly the age of his daughter. Oh, Wilson.
Out-"House": Joshua Malina is an Aaron Sorkin alum, having starred on both "Sports Night" and "The West Wing."