'21 Jump Street' (1987-91)

It's best-known now as the show that made a star of Johnny Depp (and inspired the Channing Tatum-Jonah Hill movie remake), but "21 Jump Street" also tapped into an underserved teen and young-adult audience and created a rabid fanbase -- a strategy FOX would duplicate to great success with shows like "Beverly Hills, 90210" a few years later.
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