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Aldon Smith
Odds favor Manning to reach TD milestone vs. 49ers

SANTA CLARA, Calif. Odds are the 49ers will allow three touchdown passes to Peyton Manning on Sunday night and he'll overtake Brett Favre for the NFL's all-time lead. At least that is how one online sportsbook sees it, giving Manning 9-to-5 odds to secure that milestone in a game pitting the 49ers and Denver Broncos, the past two Super Bowl runners-up. "That competitive challenge is something that I think our team, our defense, will be up for," 49ers coach Jim Harbaugh said. That defense is playing hurt, and short staffed. It practiced Wednesday without linebacker Patrick Willis (toe) and nickel back Jimmie Ward (quadriceps). Injuries limited cornerbacks Perrish...