But the answer to the question speaks to the evolution of the show.
"We don't have any scenes together," said Bialik, nominated for comedy supporting actress for the second year in a row for playing Amy Farrah-Fowler.
"That didn't shock me though," said Parsons, a two-time Emmy comedy lead actor winner as Sheldon Cooper. "Amy's taken on such a life of her own."
Parsons noted that while the show embraces the relationship between Sheldon and Amy, it isn't dependent upon moving them forward at light speed.
"In a weird way, I think that's one of the charms of the show, one of the reasons it works," Parsons said. "There's something really reliable about it. ... They (the writers) have been so careful of not trying to make giant leaps."
Said Bialik: "It's what we do. It's a great first episode, (even though) I don't think there's anything surprising."
Bialik was in better shape than she was at the same event a year ago, when she was days removed from a serious car accident that left her hand heavily bandaged.
She commented on Parsons' newfound celebrity in the world of sports. When NBA star and 2012-13 Los Angeles Laker center Dwight Howard was in the process of choosing his next team as a free agent, Parsons made a video - with a healthy supply of logic, of course - imploring Howard to join the Houston Rockets.
"I think most people don't know that Jim Parsons knows sports like you do," Bialik said to him.
Said Parsons: "Well, let's be honest, I don't think I had a whole hell of a lot to do with it. Perhaps (I did), and maybe I should just go with that and I was the tipping point. (But) they allowed me to come back to L.A. after it, so I (probably didn't) have much of an effect."
Parsons agreed that it didn't seem that many Lakers fans missed Howard all that much.
"I didn't think that they should. ... But they did know that the relationship with Howard wasn't working, don't you think? It's true. I do think this is a better situation for him - I really do."
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