It will be UCF's first home against a team from the Southeastern Conference.
The Knights have a bye this week and are not slated to practice again until Thursday.
Missouri (2-1) collected 62-10 win over Southeastern Louisiana in the season opener. The Tigers then dropped their SEC debut game 41-20 to then-No. 7 Georgia. Missouri beat Arizona State 24-20 Saturday. The Tigers will face No. 7 South Carolina Saturday before making the trip to Bright House Networks Stadium to take on UCF the following week.
Tickets for the Missouri game are available by calling 407-823-1000 or visiting UCFAthletics.com.