Stopping the high powered Arizona offense just got a little more difficult for the Colts.

The team announced Saturday night that linebacker Gary Brackett and Kelvin Hayden did not travel with the team to Arizona and hence will not play against the Cardinals Sunday night.

Brackett injured his knee near the end of the Colts' Monday night victory over Miami, and didn't practice this week. Jim Caldwell said earlier in the week that Freddy Keiaho will be the likely option to start in the middle for the injured Brackett, who so far this season has a team high 17 tackles.

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Hayden in two games made 10 tackles for the team, but injured his hamstring during the win over the Dolphins and was unable to get healthy in time for the game. Tim Jennings, Jerraud Powers, and Jacob Lacey figure to fill in at times for the cornerback.

The Colts will miss the two starters in a game which features one of the most accurate passers on the other side of the field. Arizona's Kurt Warner completed his first 15 passes against Jacksonville-an NFL record-and finished 24-of-26 for 243 yards and two touchdowns in the Cardinals' 31-17 win over the Jaguars.