Derek Richardson

Super Mario Bros. in D-minor

Super Mario Bros. in D-minor

For at least a generation of pop-culture consumers, the soundtrack of their lives has included themes from the likes of Mega Man and Super Mario.

As they've grown up, the music of video games has branched out — to solo piano, to rock concerts and to symphonic performances. Among the developments is the University of Maryland's Gamer Symphony Orchestra, whose 100-plus members will take to the stage at College Park's Clarice Smith Performing Arts Center on Saturday, May 4.

"The quality of video-game music has grown exponentially...