The shooting happened about 1:15 p.m. in the 7900 block of South St. Lawrence Avenue, fire and police officials said.
Two men wearing masks shot three people: a 20-year-old man who was dead on the scene, a 17-year-old girl in the lower back, and an 18-year-old man in the leg and lower arm, according to police.
Christopher Spraggins, 20, of the 300 block of East 76th Street, was pronounced dead at the scene while a man identified as Aaron Gaithan, 18, of an unidenitifed address, was declare dead at 2:14 p.m. at Northwestern Memorial Hospital, according to the Cook County medical examiner's office.
Police said the teen girl was taken to Advocate Christ Medical Center, where, according to Chicago Fire Department spokesman Kevin MacGregor, she was in serious condition.
The gunmen ran eastbound after the shooting and fled into a car, police said.
No arrests have been made this evening, according to police News Affairs Officer Daniel O'Brien.Four people were killed and at least 14 wounded in shootings in Chicagobetween 4:15 p.m. Friday and early Saturday morning.