With McPhee sidelined with a thigh injury and a sore right knee, the Ravens are expected to start Arthur Jones in his place.
"I'm just trying to get my knee back right," McPhee said earlier Friday. "I'm pretty banged-up, nicks and bruises."
Ngata didn't practice for the second consecutive day due to a right shoulder injury. He's also dealing with a sprained right medial collateral ligament.
Ngata is considered likely to play, but not take a full workload Sunday.
The injuries to McPhee and Ngata increase the likelihood that young defensive linemen Bryan Hall and DeAngelo Tyson will be active for the second consecutive game after they combined for four tackles on 46 snaps in a 43-13 loss to the Houston Texans.
Meanwhile, wide receiver LaQuan Williams was added to the injury report as questionable with a previously undisclosed ankle injury.
The Ravens' expanded injury report, much larger now that they've been fined $20,000 for failing to list Pro Bowl free safety Ed Reed with a torn labrum in his shoulder, is up to 19 players.
The Ravens also added wide receiver Tandon Doss as probable with an illness.
Besides Reed and Doss, the following players are listed as probable for Baltimore: wide receiver Jacoby Jones (foot), cornerback Jimmy Smith (groin), cornerback Chykie Brown (ankle), tight end Ed Dickson (hand), linebacker Dannell Ellerbe (hand), safety James Ihedigbo (hand), nose guard Ma'ake Kemoeatu (knee), offensive tackle Bryant McKinnie (hip flexor), offensive tackle Michael Oher (ankle), offensive tackle Kelechi Osemele (sprained right ankle), safety Bernard Pollard (ribs), outside linebacker Terrell Suggs (Achilles tendon), defensive tackle DeAngelo Tyson (foot) and offensive guard Marshal Yanda (shoulder).
Meanwhile, the Browns ruled out cornerback Dimitri Patterson (ankle), listed defensive lineman Ahtyba Rubin (calf) as doubtful Middle linebacker D'Qwell Jackson (Maryland) is questionable with a foot and toe injury, and wide receiver Josh Cooper is questionable with a thigh injury.
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