Osemele will have season-ending back surgery for a herniated disk. He's been replaced in the starting lineup at left guard by A.Q. Shipley.
Jackson returns from an eight-game suspension for his second violation of the NFL performance-enhancing drug policy. He has been practicing this week under a roster exemption after being activated from the reserve-suspended list, with the exemption now lifted.
Jackson has been suspended twice for unauthorized use of Adderall, a medication that heightens concentration and is used to treat attention-deficit hyperactivity disorder.
The 2012 fifth-round draft pick from Cal-Poly served a four-game suspension as a rookie, and this latest suspension cost him eight $28,235 game checks from his $480,000 base salary -- a total loss of $225,882.
"Definitely, it's been a rough first two years with that kind of stuff," Jackson told The Baltimore Sun this week, adding that he now has the required approval for the medication. "From here on out, I've grown as a person and as a man, and they're not going to have any problems out of me."
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